5-Amino-1MQ

5-Amino-1MQ is a small-molecule research compound that blocks an enzyme called NNMT (nicotinamide N-methyltransferase). It is best known in metabolic and fat-cell research, and what sets it apart is that it can slip across cell membranes to reach its target inside the cell.

It also has a solid research base, with studies looking at how blocking NNMT shifts the way cells handle nicotinamide and related methyl-group chemistry (Neelakantan et al., 2018, Biochemical Pharmacology). That is why it often turns up as a go-to reference compound in this area.

Research Applications

Supplied as a lyophilized powder for stability.