Peptide Stability Calculator

Estimate how long a research peptide stays stable, based on its form, storage temperature, and pH. For laboratory research use only.

The short version

Peptides degrade over time, but how fast depends on a few things: how cold they are kept, the pH, exposure to light, and whether they are a dry powder or a solution. This page explains those factors, then gives a rough stability estimate for your storage conditions. Everything here is for laboratory research use only.

Estimate your stability window

Pick the form, temperature, and pH, and the estimator does the rest.

Stability estimator

For informational purposes in research conditions only.

Pick all three options above to see an estimate.

This is a general research estimate based on typical peptide behaviour, not a guarantee for any specific compound. Other factors such as UV light and repeated freeze-thaw cycles also affect stability. Always follow the Certificate of Analysis. For laboratory research use only.

What affects peptide stability

The four things that decide how long a peptide keeps.

Temperature. Cold slows the chemical reactions that break peptides down. A freezer (-20°C) is best for long storage; a fridge is fine short term. Avoid repeated freeze-thaw cycles.
pH. Very acidic or very alkaline conditions speed up breakdown. Neutral pH (around 6-7) is the most stable for most sequences.
Light and oxygen. UV light and air can accelerate degradation. Keep peptides in the dark with the vial properly closed.
Form. A freeze-dried (lyophilized) powder lasts far longer than the same peptide once it has been reconstituted into a solution.

For the full picture, see the storage and reconstitution guide, or browse research-grade peptides supplied at 99% HPLC purity with a COA included.

Stability estimates are general research guidance only, not a guarantee for any specific batch. All Pepcore peptides are supplied for laboratory research use only, and are not for use in people or animals.