KPV 10 mg

KPV 10mg peptide is a short melanocortin-derived tripeptide composed of lysine, proline, and valine. As the C-terminal fragment of α-melanocyte-stimulating hormone (α-MSH), it is widely studied in inflammation-focused research for its effects on epithelial signaling, immune regulation, and barrier-support pathways. Due to its low molecular weight and straightforward structure, KPV 10mg peptide is commonly used in laboratory models that examine peptide transport, cytokine modulation, and tissue-response mechanisms linked to inflammatory stress.

Preclinical studies have shown that KPV can reduce inflammatory signaling in epithelial and immune cells, including suppression of NF-κB and MAP kinase pathway activation, while also lowering pro-inflammatory cytokine output. Research has further demonstrated that KPV is transported into cells through the PepT1 peptide transporter, which has made it especially relevant in studies of intestinal inflammation, mucosal biology, and peptide-based modulation of epithelial immune responses (Kannengiesser et al., 2008 — Inflammatory Bowel Diseases; PubMed).

Beyond gut-focused models, KPV has also been investigated in broader anti-inflammatory and tissue-repair research. Reviews of melanocortin-derived peptides attribute a substantial part of the anti-inflammatory activity of α-MSH to the KPV sequence, while additional experimental work has linked KPV to antimicrobial relevance and corneal epithelial wound-healing responses. Together, these findings have positioned KPV as a research compound of interest in studies involving epithelial recovery, inflammatory balance, and localized cellular repair processes (Bonfiglio et al., 2006 — Peptides; Luger et al., 2007 — Journal of Molecular Medicine).

The peptide is supplied as a lyophilized powder to ensure optimal stability during storage and handling.