Mazdutide 10 mg

Mazdutide is a next-generation, long-acting dual-receptor agonist engineered to simultaneously activate the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR). This dual-pathway design allows Mazdutide to regulate glucose metabolism and energy balance through complementary physiological mechanisms, positioning it as a promising research compound in metabolic disease studies.

Through GLP-1R activation, Mazdutide enhances glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying, and promotes satiety. In parallel, GCGR activation increases lipolysis and energy expenditure while reducing hepatic fat accumulation. Together, these mechanisms support both glycemic control and sustained weight reduction.

(Ji et al., 2023 — eClinicalMedicine).

Beyond metabolic regulation, Mazdutide has demonstrated additional benefits in experimental and clinical research, including improvements in hyperuricemia, blood pressure regulation, and cardiovascular risk markers.

The peptide is supplied as a lyophilized powder to ensure optimal stability during storage and handling.