5-Amino-1MQ 50 mg

5-Amino-1MQ 50mg peptide is a research-grade small-molecule compound studied for its selective inhibition of nicotinamide N-methyltransferase (NNMT), an enzyme involved in nicotinamide metabolism, methyl-donor balance, and broader cellular energy regulation. Published studies describe 5-amino-1MQ as a membrane-permeable NNMT inhibitor with activity in adipocyte and metabolic research models, making it a relevant laboratory compound for investigating the relationship between NNMT signaling, adiposity, and metabolic homeostasis.

Research interest in 5-Amino-1MQ 50mg peptide centers on how NNMT inhibition may influence lipid metabolism, adipocyte biology, and insulin-related metabolic pathways. Primary work has shown that 5-amino-1MQ inhibited NNMT with micromolar potency, increased cellular NAD+ and SAM-related metabolic balance in experimental systems, and reduced body weight and adipose tissue mass in diet-induced obesity mouse models. These findings make 5-amino-1MQ a useful research tool for studies focused on obesity-related metabolism, adipose expansion, and the biochemical consequences of suppressing NNMT activity (Neelakantan et al., 2018 — Scientific Reports).

Current research applications for 5-Amino-1MQ 50mg peptide include metabolic disease models, obesity-related pathway studies, methyltransferase-focused experiments, and broader investigations into NAD+ and methyl-donor metabolism. Review literature also places NNMT within a wider framework of metabolic syndrome, insulin resistance, and cancer-associated metabolic dysregulation, supporting ongoing interest in NNMT inhibitors such as 5-amino-1MQ for mechanistic research. More recent animal work has additionally reported that NNMT inhibition with related 5A1MQ treatment limited body-weight gain, improved glucose tolerance and insulin sensitivity, and reduced hepatic steatosis in diet-induced obesity models, further reinforcing the value of this pathway in metabolic research (Babula et al., 2024 — Diabetes, Obesity and Metabolism; Liu et al., 2021 — Frontiers in Endocrinology).

The peptide is supplied as a lyophilized powder to ensure optimal stability during storage and handling. COA included with every order. See also: AOD-9604, Cagrilintide, Tirzepatide