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Cortagen is a synthetic short-chain peptide bioregulator built from four amino acids in the sequence Ala-Glu-Asp-Pro. It is best known in research for how it is studied alongside cerebral cortex tissue, and its very compact structure is what makes it a handy tool for peptide-signaling work.
It comes from the well-documented Khavinson peptide-bioregulator line, which has a long track record in the research literature (Khavinson & Anisimov, 2009). That history is why it keeps turning up as a reference compound in this field.